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Digital Subscriptions > Healthy Magazine > June/July 2019 > YOU COME OFF ANTIDEPRESSANTS?


Around one in six of us currently use antidepressants, with 20 per cent likely to face side effects when they stop. Yet understanding of what can happen when medication ceases is often lacking, says Professor Peter Kinderman

PETER KINDERMAN is professor of clinical psychology at the University of Liverpool and former vice-president of the British Psychological Society

There are several types of antidepressant medication, most of which act on neurotransmitters in the brain to affect the availability of serotonin, which is thought to contribute to motivation and our brain’s reward mechanisms. Selective serotonin reuptake inhibitors (SSRIs, such as Prozac) are commonly prescribed, and the theory is that SSRIs prevent serotonin being reabsorbed after being used to trigger a nerve signal in the brain, so there’s more of it available for the next neural activity. In reality, we’re not entirely sure how they work or whether they’re genuinely effective as there is no way to test serotonin levels in the brain and lots of chemicals can raise mood.

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About Healthy Magazine

Ever thought about stripping back your beauty regime? From eco-cosmetics to zero waste routines, we’ve explored all the latest natural beauty innovations in our #NakedBeauty issue. Plus, we investigate the Instagram wellness scammers, question whether the perfect diet exists, and delve into the fitness industry’s issue with inclusivity. Our food sections champions pasta and puds, along with with some seriously tempting ayurvedic recipes, and we learn how to keep our core in good shape in the healthy clinic. Find all this and more in the brand new issue of Healthy!