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Digital Subscriptions > Women’s Running > Jan-18 > IDENTIFYING BREAST CANCER RISK



Two new studies, published in the journal Nature, have given scientists a deeper insight into genetic susceptibility to breast cancer. The two studies looked at data on 275,000 women, and were carried out by researchers from several international institutions, including the University of Cambridge in the UK and the University of Washington School of Public Health in the US. In the larger study, researchers looked at small variations in DNA, known as single nucleotide polymorphisms (SNPs), some of which are more common in people who have a specific condition (such as breast cancer). Researchers identified SNPs in 65 new regions of DNA associated with an increased risk of breast cancer. They also found 700 genes that could be responsible for the links. The second, smaller, study identified a further seven variations associated with an increased risk of oestrogenreceptor negative breast cancer – a type of breast cancer that is hard to treat. Researchers said the results “will improve the use of genetic risk scores for individualised screening and prevention.”

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About Women’s Running

With the festive season approaching, life is about to get busy. That’s why, this issue, we’re helping you ensure you keep up your running over the festive period with our Christmas Survival Guide, including a four-week training plan, achievable no matter how busy your schedule. Wellness is at the centre of the issue: you’ll find information from our resident GP on how to ensure you’re getting enough iron in your diet as a female runner – and spot the warning signs of a deficiency – as well as essential advice on running through pregnancy from coach Laura Fountain, as she looks at why it’s so essential for pregnant runners to listen to their bodies and focus on their own individual journeys. If you’re finding it difficult at the moment to concentrate on – and look after – yourself a little bit more, then don’t miss cover star Karen Lewing’s story; find out how she transformed her life – and her wellbeing – when she did just that. And if that’s enough to encourage you to make more time for you – and your running – next year, don’t miss contributing editor Tina Chantrey’s feature on the benefits of paid-for coaching…2018 might just be the year you take your running to the next level.