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118 MIN READ TIME

Losing the war on bugs

ELIZABETH PISANI

In the infectious disease wards of Ho Chi Minh City’s main hospital for tropical illnesses, patients are arranged behind plate-glass windows like mannequins in a department store. Those that are conscious stare blankly through the glass that separates them and their frightening pathogens—cryptococcal meningitis, perhaps, or septicaemia—from the efficient hum of nurses and orderlies on the ward. A runner comes in and hands a doctor a sheaf of papers, the latest batch of results from the microbiology lab.

For the glassed-in patients—the hospital’s most serious cases— these reports are rarely encouraging. The pathogens that have colonised their blood, lungs, or tissues have evolved their way around every drug that could have been used to combat them. And researchers working on the frontline of resistance blame the mutant bugs, in part, on fake and second-rate medicines.

This may be happening far away, but it is the west’s problem too. In these days of global tourism, travel and migration, drugresistant bacteria are highly mobile. “Humans think a lot of themselves,” said Paul Newton, professor of tropical medicine at Oxford University, who works out of a microbiology lab in Vientiane, the capital of Laos. “But in fact we’re really just exoskeletons for bacteria. They take cheap flights as often as we do.”

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