Compatibility
Will it fit in with your computer system and beliefs?
Not all of these VM options are completely open source and that can affect compatibility with your system, both in a philosophical way and at a more pragmatic level. Aqemu, Virt-manager and Gnome Boxes are all based on Qemu and are completely open source. Their hardware interface is through modules included in the standard Linux kernel and should work on just about all distros. The only time you may run into problems is if the KVM hardware acceleration isn’t enabled on your computer, which is turned on and off in the BIOS settings menu.