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RESEARCH AND A GREATER understanding of depression have highlighted that it is not solely a disease of cognitive origin. Indeed, studies reveal the role of inflammation as an underlying pivotal development factor. This management process is one that, in part, relies on the health of the gut. Having a healthy microbiome – the trillions of microbes in the gut – helps keep the barrier of the gut functioning well. This means allowing substances that should be moving in and out of the gut to pass by without hassle, while blocking those that should stay within the confines of the gut. If this is breached, it can lead to substances such as bacteria and proteins from food sneaking out of the gut and creating a wider inflammatory reaction from the immune system, which has a more systemic e€ ect.